The John David Mooney Foundation stands in the heart of Chicago's historical art district.

The Foundation is based at 114 West Kinzie Street, where Chicago's artists and independent galleries first carved out their neighborhood, now called "River North." Adjacent to the Loop business district and nestled between the Merchandise Mart and the IBM building, the Foundation resides in the cultural and design heart of Chicago. The building itself has historical significance, since its construction in 1871 indicates that it is one of the oldest post-fire buildings in Chicago. Serving a wide range of the public, it is at once a local and global destination for those seeking innovative and contemporary international art.